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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TPX2 All Species: 15.45
Human Site: T369 Identified Species: 34
UniProt: Q9ULW0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9ULW0 NP_036244.2 747 85653 T369 K I C R D P Q T P V L Q T K H
Chimpanzee Pan troglodytes XP_001153533 746 85517 T368 K I C R D P Q T P V L Q T K H
Rhesus Macaque Macaca mulatta XP_001109645 746 85683 T368 K I C R D P Q T P V L Q T R H
Dog Lupus familis XP_850934 748 86144 T370 K I S R D P Q T P V L Q T K Q
Cat Felis silvestris
Mouse Mus musculus NP_082385 745 85876 I371 A R D P Q T P I L Q T K Y R T
Rat Rattus norvegicus NP_001101260 744 85432 I369 V R D P Q T P I L Q T K Y R A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516385 623 69684 E340 M R G I T R D E D E K E E E A
Chicken Gallus gallus NP_989768 739 85048 P368 R L T N P K T P V L Q T K H R
Frog Xenopus laevis NP_001086751 715 81991 P349 Q T K Q R H R P T T C K S A A
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798362 948 108486 T569 P R L T H P K T P N L E C R N
Poplar Tree Populus trichocarpa XP_002327911 811 91572 E377 L T L T R P K E P E F E T A Q
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 97.5 90.3 N.A. 79.2 79.1 N.A. 40.1 57.5 53.8 N.A. N.A. N.A. N.A. N.A. 31.6
Protein Similarity: 100 99.3 98.6 93.9 N.A. 87.6 87.4 N.A. 53 72.5 70 N.A. N.A. N.A. N.A. N.A. 49.4
P-Site Identity: 100 100 93.3 86.6 N.A. 0 0 N.A. 0 0 0 N.A. N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 100 100 86.6 N.A. 13.3 13.3 N.A. 13.3 20 33.3 N.A. N.A. N.A. N.A. N.A. 53.3
Percent
Protein Identity: 20.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 39.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 33.3 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 0 0 0 0 0 19 28 % A
% Cys: 0 0 28 0 0 0 0 0 0 0 10 0 10 0 0 % C
% Asp: 0 0 19 0 37 0 10 0 10 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 19 0 19 0 28 10 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 10 10 0 0 0 0 0 0 0 10 28 % H
% Ile: 0 37 0 10 0 0 0 19 0 0 0 0 0 0 0 % I
% Lys: 37 0 10 0 0 10 19 0 0 0 10 28 10 28 0 % K
% Leu: 10 10 19 0 0 0 0 0 19 10 46 0 0 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 10 % N
% Pro: 10 0 0 19 10 55 19 19 55 0 0 0 0 0 0 % P
% Gln: 10 0 0 10 19 0 37 0 0 19 10 37 0 0 19 % Q
% Arg: 10 37 0 37 19 10 10 0 0 0 0 0 0 37 10 % R
% Ser: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % S
% Thr: 0 19 10 19 10 19 10 46 10 10 19 10 46 0 10 % T
% Val: 10 0 0 0 0 0 0 0 10 37 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 19 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _